Percutaneous laser application using the SpyGlass system in a patient with intrahepatic lithiasis, liver cirrhosis, and surgically altered anatomy.

system in a patient with intrahepatic lithiasis, liver cirrhosis, and surgically altered anatomy A 35-year-old woman underwent a Rouxen-Y hepaticojejunostomy in 2001 for a bileduct injury thatoccurredduringacholecystectomy for cholelithiasis. After the surgery, she began to experience episodes of relapsing cholangitis, approximately once a year, which were treated with antibiotics. However, from 2012 onwards, the episodes of cholangitis increased in frequency to five or six episodes per year, including some episodes that required prolonged hospitalization of up to 2 months. In 2014 she was referred to our hospital, where she was found to have clinical evidence of chronic liver disease that was classified as secondary biliary cirrhosis, and magnetic resonance cholangiopancreatography (MRCP) revealed multiple left intrahepatic stones (●" Fig.1). Endoscopic retrograde cholangiopancreatography (ERCP) was not attempted by enteroscopy because of the lack of the necessary device and accessories. The patient was not a candidate for left hepatectomy because of chronic liver disease, so she was placed on a waiting list for liver transplantation. Because of the persistence of her cholangitis, we decided to attempt percutaneous cholangioscopy with the single-operator direct-visualization SpyGlass system (Boston Scientific Inc., Natick, Massachusetts, USA) and laser application. Initially, a percutaneous 8-Fr catheter was placed radiologically to access the left bile duct (●" Fig.2). After 3 weeks, the SpyGlass systemwas used and laser lithotripsy was applied (●" Fig.3; ●" Video 1), with the stonefragmentsbeing removed inan antegrade fashion using the balloon of a biliary extraction catheter (Cook Medical, Inc., Winston Salem, North Carolina, USA). On follow-up MRCP, no evidence of intrahepatic stones was observed (●" Fig.4). The clinical outcome was successful, and the patient has had no new episodes of cholangitis in 10 months of follow-up. Surgery has traditionally been considered the best option for intrahepatic stones [1]. Although enteroscopy-assisted access is an acceptable option to treat intrahepatic cholelithiasis, lack of equipment may preclude this option. Percutaneous cholangioscopy is also an acceptable option, especially in the presence of difficult intrahepatic stones or distal bile duct stenosis [2]. Other access options have included transgastric and percutaneous transhepatic rendezvous maneuvers [3]. Fig.1 Magnetic resonance cholangiopancreatography (MRCP) image showing a left intrahepatic stone (arrow).